Thame is a market town and civil parish in Oxfordshire, about 9 miles (14 km) east of the city of Oxford and 7 miles (11 km) southwest of the Buckinghamshire town of Aylesbury. It derives its toponym from the River Thame which flows along the north side of the town. The parish includes the hamlet of Moreton south of the town. The 2011 Census recorded the parish's population as 11,561.

Thame was founded in the Anglo-Saxon era and was in the kingdom of Wessex.